In connection with amlodipine: severe hypotension; shock (including cardiogenic shock); obstruction of the outflow tract of the left ventricle (e.g. high grade aortic stenosis); haemodynamically unstable heart failure after acute myocardial infarction.
In connection with bisoprolol: Acute heart failure or during episodes of heart failure requiring i.v. inotropic therapy; Cardiogenic shock; Second or third degree AV block (without a pacemaker); Sick sinus syndrome; Sinoatrial block; Symptomatic bradycardia; Symptomatic hypotension; Severe bronchial asthma; Severe forms of peripheral arterial occlusive disease and severe forms of Raynaud's syndrome; Untreated phaeochromocytoma (see Precautions); Metabolic acidosis.
In connection with Concor AM: Hypersensitivity to amlodipine, dihydropyridine derivates, bisoprolol and/or to any of the excipients listed (see Description).